The immediate cause of Hidradenitis Suppurativa is clogging of the apocrine glands, due to dead skin cells become trapped in the gland, over production of oil, or bacterial accumulation. This will cause the plug to swell with pus formation. What causes this simple blockage to progress into a full blow Hidradenitis Suppurativa case is still debated, however, possible theories include an auto-immune reaction, hormone imbalances and genetic disorders. It is also known that excessive sweating and being overweight will increase the risk of developing the condition. Furthermore, wearing tight clothing, excessive shaving, using lithium medications and hot humid climates have been identified as triggering factors.

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